Medical Knowledge


Infant baby and children easily suffer from infection diseases, especiallly respiratory infection, because baby’s organs have not developed maturely yet. Function of organs have not worked fully. In spite of drug administration through any route such as oral route, injection, topical route, etc. drug are absorbed into the body, metabolised in the liver and eliminated via the kidneys whereas function of the liver and kidneys in baby are still very weak. It must be very cautious while using drug for baby because of the rick of respiratory inhibition.

Infant baby, children, pregnant women and lactating women strongly need to be cared about drug using while suffering from acute respiratory infection, especially in case of cough. Cough results from different causes such as bacteria, virus, lung inflammation, allergy or flu in case of climate change. Cough may awaken baby easily, make baby jump or even cause milk splitting, or food vomitting. Therefore, if prolonged cough is not treated or treated with unappropriate anti – tussive drugs, health of baby and pregnant women is directly effected.

According to the philosophy “Vietnamese pharmaceutical products for Vietnamese people”, there are many medicinal herbs that is highly efficacious for treatment of cough. For a long time, it was recommended by the health branch that people should use medicinal herbs, traditional vietnamese ingredients which are safe and are widely handed down in the folk medicine such as folium plectranthi, dried tangerine skin, apricoat leaves, spring onion, Cortex Oroxylum indicum, honey, etc. for treating cough.

In 1983, the product “Siro ASTEX” was researched and prepared by the group of Pharmacists in Pharmacy Department – Children Hospital, it was used for treatment inside Children Hospital 1 with total amount of 48,000 litter for hospital patients and 3,600,000 bottles for external  patients. “Siro ASTEX” is prepared in form of syrup with herbal fragrange, sweet taste, is approriate for use in children and affects as anti-biotic against respiratory bacteria. Besides, it affects as antiseptic for respiratory tract, anti-allergy, expectorant and cough relief.

Overall treatment results show that “Siro ASTEX” is efficacious for treating and reducing the symptoms of cough in children and in the programme for treatment of acute respiratory infection in children at hospital in 20 years from 1985 to 2005.

Since September 2009, Children Hospital 1 have authorised OPC Pharmaceutical Joint Stock Company to produce “Siro Astex” and “Siro Astex” was released to the market with the name “Siro HoAstex”. As soon as it was launched into the market, HoAstex was possitively regconised, its sale placed among top 5 of OPC product’s and honorably granted the title “Star of Vietanamese Medicine 104” by Minitry of Health.

Folium plectranthi                                          45.00g
Cortex Oroxylum indicum                             11.25g
Cineol (Cineolum)                                           0.08g
Excipients (sugar, water)                         s.q.f. 90ml

  • Treat cough, sore throat, bronchitis, asthma.


  • Infant baby to children below 2 years of age: 2 – 5 ml each time, 3 times per day.
  • Children from 2 to below 6 years of age: 5 – 10 ml each time, 3 times per day.
  • Children over 6 years of age: 15 ml each time, 3 times per day.


By Doctor Linh Nguyen Thi Thuy - Translate by Master Pharmacist Dan Tran Ngoc

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